Research Topic · Peer-Reviewed

Alzheimer s Disease

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterized by a gradual decline in memory, reasoning, language, and the ability to carry out everyday activities. It is associated with pathological changes in the brain, including the accumulation of amyloid pl…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 33× across the literature 🔖 ISSN 2998-4211 🗓 Reviewed July 2026

Overview

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterized by a gradual decline in memory, reasoning, language, and the ability to carry out everyday activities. It is associated with pathological changes in the brain, including the accumulation of amyloid plaques and neurofibrillary tangles, neuronal loss, and atrophy of affected regions such as the medial temporal lobe. The disease usually emerges in later life and advances over years, often passing through stages of mild cognitive impairment before reaching more severe dementia. There is currently no cure; available interventions aim to manage symptoms, support function, and improve quality of life for patients and caregivers. Work appearing in this journal reflects the breadth of contemporary Alzheimer's research, including efforts at early prediction and biomarker discovery, non-pharmacological interventions for problems such as disrupted sleep, and the neurobiology underlying behavioral symptoms like aggression and agitation. Other contributions examine caregiver knowledge and misconceptions, the overlap between depression, cognitive impairment, and temporal lobe atrophy, and molecular mechanisms involving circular RNAs and inflammatory markers. Across these strands, key themes include diagnosis and staging, distinguishing Alzheimer's from related conditions, caregiver education and support, and the search for modifiable risk factors and treatments that may slow or alter disease progression.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

JALR. New Journal, Old questions, Fresh insights

Paganelli RobertoCorresponding author
Department of Medicine & Sciences of Aging, University “G. d’Annunzio” of Chieti-Pescara, Italy
Exact topic Alzheimer's Research and Therapy doi:10.14302/issn.2998-4211.jalr-17-1884
2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603
2021

How this research is being cited

The 12 articles above have been cited 33 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Alzheimer s Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Alzheimer's Research and Therapy (ISSN 2998-4211).

Journal editorial board
Aysun Cetinyurek Yavuz · Netherlands Elvis Freeman Acquah · Australia Silvia Ingala · Denmark

This page summarises published research for orientation; it is not medical or professional advice.