Overview
Glycolysis is the central metabolic pathway by which a molecule of glucose is broken down through a series of enzyme-catalyzed reactions into two molecules of pyruvate, yielding a net gain of energy in the form of ATP along with reducing equivalents in the form of NADH. Occurring in the cytoplasm of virtually all cells, glycolysis does not require oxygen and therefore serves as a key energy source under anaerobic conditions, while also providing precursors that feed into other pathways. Under aerobic conditions the resulting pyruvate is further oxidized in the mitochondria, whereas under anaerobic conditions it is converted to lactate or, in some organisms, ethanol, regenerating the cofactors needed to sustain the pathway. The ten steps of glycolysis are tightly regulated by key Enzymes, making it a focal point for understanding cellular energy metabolism. Altered glycolytic activity is biologically significant in many contexts, including the reprogrammed metabolism of cancer cells, which often rely heavily on glycolysis even in the presence of oxygen. Research relevant to this topic, within the scope of Enzymes, includes work on targeting cell metabolism in chronic lymphocytic leukaemia and studies of redox Enzymes and glucose-derived metabolites and their reactions. This page gathers peer-reviewed, open-access research relevant to glycolysis, enzyme function, and cellular energy metabolism.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Targeting Cell Metabolism in Chronic Lymphocytic Leukaemia (CLL); Aviable Therapeutic Approach?
Correlating 13C Isotope in Oligomeric Proanthocyanidins with their Anticancer Properties
SARS-CoV-2 affected cells Pathogeny and Therapy
Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer
Non-Enzymatic Methylglyoxal Formation From glucose Metabolites and Generation of Superoxide Anion Radical During Methylglyoxal-Dependent Cross-Links Reaction
The Impact of Nutrients on Diabetes
Increased Level of Lactate Dehydrogenase Correlates with Disease Growth in Algerian Children with Lymphoma
Amino Acids and their Derivatives in Pathogenesis and Treatment of Liver Diseases
The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a
Hepatic Metabolomics Profiling of Cyprinus Carpio after Acute Cypermethrin Toxicity
Application of Nanotechnology for the Preservation of Red Blood Cells
How this research is being cited
The 12 articles above have been cited 61 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Antioxidants
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2025 · Chemical Engineering Journal
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Janka Vašková et al. · 2025 · Antioxidants
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2025 · Oncology Letters
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2025 · Current Drug Delivery
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2024 · Reviews in Cardiovascular Medicine
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2024 · Current Issues in Molecular Biology
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V. Lankin et al. · 2024 · Reviews in cardiovascular medicine
A sample of recent works citing this journal's research on Glycolysis, linking to each citing work.