Research Topic · Peer-Reviewed

Thrombosis

Thrombosis is the pathological formation of a blood clot, or thrombus, within a blood vessel or the heart, obstructing circulation at the site of formation or, if dislodged, producing embolism downstream. It is classically understood through Virchow's triad, the three interacting predisposing factors of venous stasi…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 60× across the literature 🔖 ISSN 2329-9487 🗓 Reviewed July 2026

Overview

Thrombosis is the pathological formation of a blood clot, or thrombus, within a blood vessel or the heart, obstructing circulation at the site of formation or, if dislodged, producing embolism downstream. It is classically understood through Virchow's triad, the three interacting predisposing factors of venous stasis, endothelial or vascular injury, and hypercoagulability of the blood. Arterial thrombosis, typically platelet-rich and often superimposed on ruptured atherosclerotic plaque, causes myocardial infarction and ischaemic stroke, whereas venous thrombosis, characteristically fibrin- and red-cell-rich, manifests as deep vein thrombosis and pulmonary embolism. Inherited and acquired thrombophilias, including Factor V Leiden and other coagulation abnormalities, raise thrombotic risk, while malignancy and its treatment can disturb haemostatic balance. Thrombosis may also arise at unusual sites and in association with prosthetic surfaces or surgical reconstruction. Studies in this area examine postpartum ovarian vein thrombosis, jugular and cerebral venous sinus thrombosis, the failure of vascular grafts, hypercoagulability complicating acute leukaemia, inherited bleeding and coagulation disorders, and the role of Factor V Leiden. The field integrates haemostasis, vascular biology, genetics, and clinical medicine to understand clot formation, its predisposing conditions, and the spectrum of arterial, venous, and site-specific thrombotic disease and their sequelae.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 60 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Thrombosis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hypertension and Cardiology (ISSN 2329-9487).

Journal editorial board
Hatori Nobuo · Japan Gregor Leibundgut · Switzerland Yuejin Li · United States

This page summarises published research for orientation; it is not medical or professional advice.