Overview
Replication, in molecular biology, is the process by which genetic material is copied so that information can be transmitted to daughter cells or progeny particles. In cellular organisms it refers to the semiconservative duplication of DNA prior to cell division, in which each strand templates synthesis of a complementary strand; in viruses it denotes the intracellular reproduction of viral genomes and the assembly of new infectious particles. Fidelity, regulation, and the control of replication are central to genome stability, development, and disease. The research collected here engages replication and the broader machinery of genetic information across several contexts. Viral replication features prominently, including narrative review of SARS-CoV-2 and analytical modelling of its intracellular life cycle, alongside immunological strategies directed against HIV-1. Genome integrity and its disruption appear in work on oxidative telomere attrition and biological aging and on gene-expression changes underlying resistance to apoptosis in cancer cells. Regulatory and sequence-level analyses are represented by computational study of regulatory SNPs and transcription-factor binding linked to high-altitude adaptation, and by examination of genes involved in tumour formation. The collection also reflects evolutionary and modelling perspectives on heredity and disease. Together these works situate replication within the wider biology of genetic information transfer, emphasising how the accurate copying and regulation of genomes underpins both normal physiology and the pathology of infection and cancer.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Novel Coronavirus 2019 (COVID-19): A Narrative Review
Raising HLA-E-Restricted HIV-1-Specific Immune Responses Through T Cell Vaccination: A Hypothesis
Genes in Tumor Formation
Computational EPAS1 rSNP Analysis, Transcriptional Factor Binding Sites and High Altitude Sickness or Adaptation
Review: The Role of Human Papillomavirus in Virus-Induced Carcinogenesis
First Analytical Solution of Intracellular life Cycle of SARS-CoV-2
A General Approach to Modeling Covid-19
Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis
High-Throughput Complex Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development
Conservation, Creation, and Evolution: Revising the Darwinian Project
How this research is being cited
The 12 articles above have been cited 52 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · International Journal of Biometeorology
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2025 · Communications Biology
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2025 · Artificial Life
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J. Grijalva-Avila et al. · 2025 · Metabolites
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2025 · Metabolites
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2025 · Scientific Reports
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2025 · Communications Biology
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2025 · Ethical Review of Social Sciences
A sample of recent works citing this journal's research on Replication, linking to each citing work.