Research Topic · Peer-Reviewed

Inflammatory Pain

Inflammatory pain is a form of nociceptive pain that arises when tissue injury or infection triggers the release of inflammatory mediators, including prostaglandins, bradykinin, histamine, cytokines, and nerve growth factor, which sensitize peripheral nociceptors and lower their activation threshold. This peripheral…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 30× across the literature 🔖 ISSN 2688-5328 🗓 Reviewed July 2026

Overview

Inflammatory pain is a form of nociceptive pain that arises when tissue injury or infection triggers the release of inflammatory mediators, including prostaglandins, bradykinin, histamine, cytokines, and nerve growth factor, which sensitize peripheral nociceptors and lower their activation threshold. This peripheral sensitization, together with central sensitization in the dorsal horn, produces hyperalgesia and allodynia and accounts for the heightened, persistent pain accompanying conditions such as arthritis, inflammatory bowel disease, and post-surgical tissue trauma. Pharmacological control targets these pathways through nonsteroidal anti-inflammatory drugs, which inhibit cyclooxygenase-mediated prostaglandin synthesis, alongside novel analgesic and anti-inflammatory agents and adjunctive strategies. Research relevant to this topic includes the development of a novel N-pyrrolylcarboxylic acid derivative as a potential analgesic and anti-inflammatory drug, the effect of capsaicin in intestinal bowel disease, and auricular vagus nerve stimulation that improves chronic pain while modulating pain-related cytokine levels. Further work examines analgesic procedures after joint surgery and the broader relationship between cytokine signaling and pain. The journal publishes peer-reviewed research on the molecular mediators, pharmacology, and clinical management of inflammatory and chronic pain, with attention to both established anti-inflammatory therapies and investigational compounds and neuromodulatory techniques.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

Pain between Psyche and Soma in Uro-Andrology

Pruneti CarloCorresponding author
Dept. of Medicine and Surgery, Clinical Psychology, Clinical Psychophysiology and Clinical Neuropsychology Labs., University of Parma, Italy.
International Journal of Pain Management Cited by 2 doi:10.14302/issn.2688-5328.ijp-20-3386

How this research is being cited

The 12 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Inflammatory Pain, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Pain Management (ISSN 2688-5328).

Journal editorial board
Maurizio Evangelista · Italy Anne Manyande · UNITED KINGDOM Dimos-Dimitrios Mitsikostas · Greece

This page summarises published research for orientation; it is not medical or professional advice.