Research Topic · Peer-Reviewed

Liver Cirrhosis

Liver cirrhosis is the advanced, diffuse scarring of the liver in which progressive fibrosis and regenerative nodules replace functional hepatic tissue, distorting the organ's architecture and impairing its synthetic and metabolic roles. It represents the common end stage of chronic liver injury arising from causes …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 15× across the literature 🗓 Reviewed July 2026

Overview

Liver cirrhosis is the advanced, diffuse scarring of the liver in which progressive fibrosis and regenerative nodules replace functional hepatic tissue, distorting the organ's architecture and impairing its synthetic and metabolic roles. It represents the common end stage of chronic liver injury arising from causes such as viral hepatitis, alcohol-related disease, and metabolic and fatty liver disease. A defining consequence is portal hypertension, the rise in pressure within the portal venous system that drives the formation of gastro-oesophageal and gastric varices, ascites, and the risk of variceal haemorrhage; related vascular anomalies such as isolated left gastric vein stenosis can produce similar bleeding. Chronic liver disease also predisposes to hepatocellular carcinoma, where angiogenic markers reflect tumour development on a background of hepatitis infection. Assessment combines clinical, biochemical, and imaging methods, including non-invasive measures of liver stiffness, although such measures do not always correlate with the degree of decompensation or portal hypertension. Research in this area examines the epidemiology and trends of chronic liver disease across populations, the complications of decompensation, the management of hepatitis as an underlying cause, and the diagnostic tools used to stage disease and predict outcome.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Pseudotumor Tuberculosis Of Liver: A Rare Entity

Soufi MehdiCorresponding author
Department of digestive Surgery, Faculty of medicine Oujda, University Mohammed first, Oujda -Morocco
Spleen And Liver Research Cited by 1 doi:10.14302/issn.2578-2371.jslr-14-539

How this research is being cited

The 12 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Liver Cirrhosis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Surgery Proceedings.

Journal editorial board
Sathya-Prasad Burjonrappa · United States Luigi Boni · Italy Salvador Morales-Conde · Spain

This page summarises published research for orientation; it is not medical or professional advice.