Overview
Second messenger systems are intracellular signaling pathways in which extracellular signals trigger the production of small molecules inside cells that amplify and propagate the original signal to produce specific cellular responses. Research published in Model Based Research has examined second messenger systems through mathematical and computational modeling approaches across reproductive biology and viral infection contexts. One study analyzed the signal transduction pathway of human chorionic gonadotropin, investigating how this hormone induces decidualization and prepares the uterus for embryo implantation through its intracellular signaling cascades. Additional work has applied modeling frameworks to understand the intracellular life cycle of SARS-CoV-2, providing analytical solutions that describe viral replication processes within infected cells, where second messenger-like amplification mechanisms play critical roles in viral propagation. Further modeling research has addressed broader aspects of COVID-19 pathogenesis, incorporating cellular signaling dynamics into predictive frameworks. These investigations demonstrate how mathematical modeling can elucidate the quantitative dynamics of second messenger systems, offering insights into both normal physiological processes such as reproduction and pathological conditions including viral infections, where understanding signal amplification mechanisms is essential for developing therapeutic interventions.
Research published in this journal
3 peer-reviewed articles, ranked by relevance. Each links to its DOI.
First Analytical Solution of Intracellular life Cycle of SARS-CoV-2
A General Approach to Modeling Covid-19
How this research is being cited
The 3 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Journal of Clinical Practice and Medical Research
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2025 · Journal of Clinical Practice and Medical Research
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2023 · Research Square (Research Square)
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2023 · Journal of Model Based Research
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2023 · Journal of Model Based Research
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2017 · Journal of Fertility Biomarkers
A sample of recent works citing this journal's research on Second Messenger System, linking to each citing work.