Overview
Sleep apnea and cardiovascular disease describes the well-recognized link between disordered breathing during sleep, most often obstructive sleep apnea, and disorders of the heart and blood vessels. In obstructive sleep apnea, repeated collapse of the upper airway during sleep produces cycles of reduced or absent airflow, intermittent drops in blood oxygen, and brief arousals. These cycles impose recurrent physiological stress through intermittent hypoxia and reoxygenation, surges in sympathetic nervous system activity, fluctuations in intrathoracic pressure, oxidative stress, and inflammation. Over time these mechanisms contribute to and worsen cardiovascular conditions, and sleep apnea is associated with hypertension, cardiac arrhythmias, coronary artery disease, heart failure, and stroke, as well as with the metabolic disturbances that compound cardiovascular risk. The relationship is bidirectional in clinical practice, since cardiovascular and metabolic disease and sleep-disordered breathing frequently coexist, and unrecognized apnea can undermine the management of conditions such as resistant hypertension. Cardiac function and the prevalence of sleep-disordered breathing can be evaluated using ambulatory monitoring and polysomnographic methods, while screening identifies apnea in at-risk groups, including patients with diabetes. Treatment of sleep apnea, particularly with positive airway pressure and weight reduction, aims to relieve the nightly physiological burden and to mitigate cardiovascular consequences. Understanding this connection is central to sleep medicine and to recognizing and treating apnea as part of cardiovascular risk reduction.
Research published in this journal
10 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Assessing the risk of Obstructive Sleep Apnea in Type 2 Diabetes Mellitus patients in India
Obstructive Sleep Apnea in Individuals with Down Syndrome: A Meta-Analytic Literature Review
Obstructive Sleep Apnea Treatment with Epap Nasal Devices: Physiological Principles and Limitations
Adopting High Fat Diets for Fat Loss and Improving Brain Health.
Ehlers-Danlos Syndrome and Narcolepsy: An Incidental Relationship?
Exploring the Endocannabinoid System: From Circadian Rhythms to Sleep Regulation and Potential Therapeutic Insights
How to Objectively Measure The Quality of Sleep
Narcolepsy With or Without Cataplexy In The Pediatric Population: A Systematic Review
Efficacy of a Hypocaloric Mediterranean Diet in Overweight Patients: Factors Predictive of Completion
How this research is being cited
The 10 articles above have been cited 39 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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V. Vathanophas et al. · 2025 · Congenital Anomalies
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2025 · Congenital Anomalies
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2025 · Elsevier eBooks
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Huỳnh Thiện Duyên Nguyễn et al. · 2025 · Tạp chí Y Dược học Cần Thơ
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2024 · Cureus
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2024 · Lecture notes in networks and systems
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2024 · Cureus
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2024 · Autism and child psychopathology series
A sample of recent works citing this journal's research on Sleep Apnea Cardiovascular, linking to each citing work.