Stenosis is the abnormal narrowing of a tubular anatomical structure such as a blood vessel, cardiac valve orifice, airway, or the spinal canal, which restricts the normal passage of blood, air, or nervous tissue. It may be congenital or acquired, with common acquired causes including atherosclerotic plaque depositi…
Stenosis is the abnormal narrowing of a tubular anatomical structure such as a blood vessel, cardiac valve orifice, airway, or the spinal canal, which restricts the normal passage of blood, air, or nervous tissue. It may be congenital or acquired, with common acquired causes including atherosclerotic plaque deposition, calcification, fibrosis, inflammatory or rheumatic disease, and external compression. The haemodynamic and clinical consequences depend on the site and severity: coronary and carotid stenosis impair perfusion and predispose to ischaemia and infarction; valvular stenosis, such as mitral stenosis arising from rheumatic heart disease, increases chamber pressures and can cause atrial enlargement; venous stenosis can produce collateral varices; and spinal stenosis compresses neural elements. Assessment relies on imaging and functional studies, including ultrasound, computed tomography, angiography, and electrocardiography, alongside modelling of flow and lipoprotein deposition within narrowed vessels. Management ranges from medical risk-factor control to percutaneous intervention and surgery. The peer-reviewed research collected under this topic spans severe mitral stenosis and rheumatic heart disease, percutaneous coronary intervention for complex lesions, modelling of low-density lipoprotein deposition in coronary geometry, gastric venous stenosis, and spinal and adjacent-segment narrowing, reflecting the breadth of structures and mechanisms in which pathological narrowing produces disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 12 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Stenosis, linking to each citing work.