Submit Your Systems Biology Research
Join leading molecular biologists and systems researchers publishing groundbreaking discoveries in gene regulation, protein interactions, and cellular pathway analysis
Two Convenient Submission Methods
Choose the submission method that best fits your workflow. Both options provide secure, efficient manuscript handling with full editorial support throughout the peer review process.
ManuscriptZone Portal
Our comprehensive manuscript management system designed for researchers who value complete control and real-time tracking of their submissions.
- Auto-save functionality prevents data loss
- Real-time submission status tracking
- Direct access to reviewer comments
- Guided step-by-step submission workflow
- Secure document management
- Revision tracking and version control
Quick Submission Form
A streamlined alternative for straightforward submissions when you need a faster, simpler process without account creation.
- No account registration required
- Simple one-page submission form
- Fast upload for complete manuscripts
- Ideal for straightforward submissions
- Email confirmation upon receipt
- Transferred to ManuscriptZone for tracking
Manuscript Types We Publish
Journal of Systems Biology welcomes diverse contributions advancing our understanding of molecular mechanisms, cellular systems, and biological networks. Our expert reviewers specialize in systems-level analysis and molecular biology methodologies.
Original Research Articles
Comprehensive studies on gene expression analysis, protein-protein interactions, metabolic pathway modeling, and systems-level investigations of cellular processes.
Methods & Protocols
Novel experimental techniques, computational algorithms, bioinformatics pipelines, and analytical methods for systems biology research and omics data analysis.
Systems Analysis Reviews
Comprehensive reviews of molecular pathways, regulatory networks, multi-omics integration approaches, and systems-level understanding of biological phenomena.
Computational Models
Mathematical models, network simulations, predictive algorithms, and computational frameworks for understanding complex biological systems and molecular dynamics.
Data Resources
Large-scale datasets, omics databases, annotated biological networks, and curated resources supporting systems biology research and molecular investigations.
Short Communications
Rapid reports of significant findings in molecular mechanisms, preliminary systems-level discoveries, and time-sensitive observations requiring quick dissemination.
Research Scope & Focus Areas
Our journal specializes in systems-level approaches to molecular biology, emphasizing integrative analysis of biological networks and molecular mechanisms.
Gene Regulatory Networks
Transcriptional regulation, epigenetic modifications, chromatin dynamics, and gene expression control mechanisms
Protein Interaction Networks
Protein complexes, signaling cascades, post-translational modifications, and proteome-wide interaction mapping
Metabolic Systems
Metabolic flux analysis, pathway reconstruction, enzyme kinetics, and metabolome profiling
Multi-Omics Integration
Genomics, transcriptomics, proteomics, metabolomics integration for comprehensive systems understanding
Cellular Signaling
Signal transduction pathways, receptor dynamics, second messengers, and cross-talk mechanisms
Computational Biology
Network modeling, machine learning applications, predictive algorithms, and bioinformatics tools
Pre-Submission Checklist
Ensure your manuscript meets these requirements before submission to expedite the review process and avoid delays:
Word (.docx) or LaTeX files with clear section headings and proper formatting
TIFF or EPS format, minimum 300 DPI resolution, properly labeled with descriptive captions
Omics data deposited in public repositories (GEO, ProteomeXchange, MetaboLights) with accession numbers
IRB/IACUC approval documentation for human subjects or animal studies
All authors have approved the manuscript and agreed to submission
Declaration of financial and non-financial competing interests
Computational scripts and analysis code deposited in GitHub or Zenodo
Complete citations in Vancouver or APA style with DOIs where available
Peer Review Timeline
Our transparent, efficient peer review process ensures rigorous evaluation by systems biology experts while maintaining rapid turnaround times.
Initial Screening
Editorial team reviews manuscript for scope, quality, and completeness. Plagiarism check performed using iThenticate software.
3 daysEditor Assignment
Manuscript assigned to an editor with expertise in your specific area of systems biology research for optimal evaluation.
2 daysPeer Review
Expert reviewers with specialized knowledge in molecular biology and systems approaches evaluate methodology, results, and conclusions.
21 daysEditorial Decision
Editor synthesizes reviewer feedback and makes decision: accept, minor revisions, major revisions, or reject with constructive feedback.
28 days totalRevision & Re-review
Authors submit revised manuscript addressing reviewer comments. Re-review by original reviewers ensures concerns are adequately addressed.
14 daysProduction & Publication
Accepted manuscripts undergo copyediting, typesetting, and final author proofing before immediate open access publication.
10 daysAverage Time to Publication: 60 Days
From initial submission to online publication, we maintain one of the fastest turnaround times in systems biology publishing while ensuring rigorous peer review standards.
Why Systems Biologists Choose Our Journal
Specialized Indexing
Your research gains worldwide visibility through indexing in Google Scholar, connecting it with the global scientific community.
Expert Reviewers
Peer review by active systems biology researchers with expertise in omics analysis, network modeling, and molecular mechanisms
Rapid Decisions
First decision in 21 days on average, with transparent communication throughout the entire review process
Global Open Access
Immediate worldwide accessibility with no subscription barriers, maximizing impact and citation potential
Ethical Standards
Committed to COPE publication ethics, transparent peer review, and rigorous standards. We handle misconduct allegations seriously and fairly.
APC Waivers Available
Financial support for researchers from low-income countries and unfunded studies upon request
Manuscript Preparation Guidelines
Structure Your Manuscript
Organize your systems biology research following this recommended structure for optimal clarity and impact:
- Title: Concise and descriptive, including key molecular systems or pathways investigated
- Abstract: 250-300 words summarizing objectives, methods, key findings, and systems-level implications
- Keywords: 5-8 terms including specific molecular processes, methodologies, and biological systems
- Introduction: Background on the biological system, current knowledge gaps, and research objectives
- Materials & Methods: Detailed experimental protocols, computational methods, statistical analyses, and data processing pipelines
- Results: Clear presentation of findings with appropriate figures showing network diagrams, pathway maps, or omics data
- Discussion: Interpretation of results in systems context, comparison with existing models, and broader implications
- Conclusions: Key insights into molecular mechanisms and systems-level understanding
- Data Availability: Repository accession numbers for omics datasets and computational code
- References: Comprehensive citations of relevant systems biology and molecular biology literature
Figures & Tables
High-quality visual representations are essential for systems biology research:
- Network diagrams should clearly show nodes, edges, and interaction types
- Pathway maps must include gene/protein names and regulatory relationships
- Heatmaps require proper color scales and hierarchical clustering dendrograms
- All omics data visualizations need appropriate statistical annotations
- Submit figures as separate high-resolution files (TIFF/EPS, 300+ DPI)
Ready to Submit Your Research?
Our editorial team is here to support you throughout the submission and peer review process. For technical assistance or questions about manuscript preparation, contact our support team at [email protected]
Begin Your Submission
