Journal of Developments in Mass Spectrometry

Journal of Developments in Mass Spectrometry

Journal of Developments in Mass Spectrometry – Aim And Scope

Open Access & Peer-Reviewed

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Aims & Scope

Journal of Developments in Mass Spectrometry (JDMS) publishes research advancing the fundamental chemistry, instrumentation, and analytical applications of mass spectrometry across molecular characterization, materials analysis, and chemical measurement science.

Instrumentation Development Ionization Mechanisms Proteomics & Metabolomics Structural Characterization Analytical Method Development
Scope Boundary: We do NOT consider clinical outcomes research, patient care protocols, diagnostic medicine, or therapeutic interventions. Focus must be on chemical mechanisms, molecular analysis, or instrumentation.

Research Domains

Tier 1: Core Domains

Instrumentation & Technology

  • Mass analyzer development (Orbitrap, FT-ICR, TOF, quadrupole, ion trap)
  • Ionization source innovation (ESI, MALDI, APCI, ambient ionization)
  • Ion mobility spectrometry and separation techniques
  • Detector technology and signal processing
  • Hyphenated systems (LC-MS, GC-MS, CE-MS)
  • High-resolution and tandem MS (MS/MS) methodologies
Typical fit: Development of a novel ion trap design improving sensitivity for low-abundance metabolite detection through optimized RF waveform modulation.

Molecular Characterization

  • Protein identification, quantification, and post-translational modifications
  • Small molecule structure elucidation and fragmentation pathways
  • Lipid profiling and lipidomics workflows
  • Glycan analysis and glycomics strategies
  • Isotope ratio measurements and isotopic labeling
  • Protein-ligand and protein-protein interaction mapping
Typical fit: Characterization of phosphorylation site occupancy in kinase substrates using electron-transfer dissociation MS/MS with isotope-coded affinity tags.

Chemical Analysis & Applications

  • Environmental contaminant detection and quantification
  • Food chemistry, safety analysis, and authentication
  • Pharmaceutical compound characterization and impurity profiling
  • Agrochemical residue analysis and degradation pathways
  • Forensic chemical identification and trace analysis
  • Materials characterization (polymers, nanomaterials, surfaces)
Typical fit: Quantitative analysis of pesticide metabolites in soil matrices using QuEChERS extraction coupled with UHPLC-HRMS and suspect screening workflows.

Ion Chemistry & Mechanisms

  • Gas-phase ion chemistry and reaction kinetics
  • Fragmentation mechanisms and dissociation pathways
  • Ion activation methods (CID, ETD, ECD, UVPD)
  • Ion-molecule reactions and charge transfer processes
  • Sputtering mechanisms and surface ionization
  • Computational modeling of ionization and fragmentation
Typical fit: Mechanistic investigation of radical-directed dissociation in peptide ions using density functional theory calculations validated by UVPD-MS experiments.
Tier 2: Secondary Focus

Omics Technologies

Proteomics, metabolomics, lipidomics, and glycomics workflows emphasizing analytical chemistry and molecular identification rather than biological interpretation.

Data Science & Informatics

Machine learning algorithms for spectral interpretation, database development, data processing pipelines, and software tools for MS data analysis.

Sample Preparation Chemistry

Novel extraction methods, derivatization strategies, enrichment techniques, and chemical modification approaches optimizing analyte recovery and ionization.

Imaging Mass Spectrometry

Spatial molecular mapping, tissue imaging, MALDI imaging, DESI imaging, and ion mobility imaging with focus on analytical methodology.

Bioanalytical Chemistry

Pharmacokinetic analysis, drug metabolism studies, biomarker quantification, and therapeutic monitoring emphasizing chemical measurement rather than clinical outcomes.

Structural Biology

Native MS, hydrogen-deuterium exchange, cross-linking MS, and top-down proteomics for protein structure and conformational analysis at the molecular level.

Tier 3: Emerging Areas

Artificial Intelligence Integration

Deep learning for spectral prediction, automated compound identification, real-time data processing, and intelligent instrument control systems.

Miniaturization & Portability

Miniature mass spectrometers, field-deployable instruments, point-of-need analysis systems, and microfluidic MS interfaces.

Quantum & Advanced Physics

Quantum chemistry applications in MS, advanced ion optics, novel trapping mechanisms, and fundamental physics of ion behavior.

Astrobiology & Space Science

Extraterrestrial sample analysis, space-qualified instrumentation, planetary chemistry, and astrobiology applications with focus on analytical chemistry.

Note: Emerging area submissions undergo additional editorial review to ensure alignment with core analytical chemistry focus and sufficient methodological rigor.

Out of Scope

Explicit Exclusions

  • Clinical Diagnostics & Patient Care Research focused on diagnostic protocols, clinical decision-making, patient outcomes, disease prognosis, or therapeutic efficacy without substantial analytical chemistry innovation.
  • Medical Treatment Protocols Studies primarily addressing treatment regimens, dosing strategies, clinical trial outcomes, or healthcare delivery systems. Pharmacokinetic studies must emphasize analytical methodology.
  • Biological Mechanism Studies Without MS Innovation Investigations of cellular pathways, disease mechanisms, or physiological processes where MS is merely a detection tool without methodological advancement or chemical insight.
  • Pure Bioinformatics Computational biology, genomics, transcriptomics, or systems biology research without direct connection to mass spectrometry data generation or interpretation.
  • Review Articles Without Novel Analysis General literature reviews lacking original data, critical methodological comparison, or meta-analysis of MS performance characteristics across studies.

Article Types & Editorial Priorities

Priority 1: Fast-Track Review Accelerated Editorial Processing
Original Research Articles Systematic Reviews & Meta-Analyses Methods & Protocols Instrumentation Notes
Priority 2: Standard Review Regular Editorial Timeline
Short Communications Technical Notes Data Descriptors Application Notes Perspectives & Commentaries
Rarely Considered Exceptional Circumstances Only
Opinion Pieces Case Reports Letters to Editor

These formats are considered only when presenting exceptional methodological insights, paradigm-shifting observations, or critical technical corrections to published literature.

Editorial Standards & Requirements

Reporting Guidelines

Adherence to discipline-specific standards: MIAPE for proteomics, STROBE for observational studies, ARRIVE for animal research, and CONSORT for method comparisons.

Data Transparency

Raw mass spectrometry data deposition in public repositories (PRIDE, MetaboLights, MassIVE) required for all omics studies. Method validation data must be provided.

Reproducibility

Detailed method descriptions enabling replication, including instrument parameters, software versions, statistical approaches, and quality control metrics.

Ethics & Compliance

IRB approval for human samples, IACUC approval for animal studies, appropriate biosafety protocols, and conflict of interest disclosure required.

Preprint Policy

Preprints on recognized servers (ChemRxiv, arXiv, bioRxiv) welcomed. Preprint posting does not affect consideration. Must be disclosed during submission.

Software & Code

Custom software, scripts, and algorithms must be made available via public repositories (GitHub, Zenodo) with clear documentation and version control.

Editorial Performance Metrics

21 days Median Time to First Decision
38% Acceptance Rate (2023)
45 days Acceptance to Online Publication
Open Article Processing Charges

Ready to Submit?

If your research advances mass spectrometry through instrumentation innovation, methodological development, or novel chemical applications, we want to hear from you.

Submit Your Manuscript